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Dear Members and Colleagues,
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Please join us at BCCN for our first lecture of the summer semester with Andrew Sharott (Oxford), on April 15. This talk is hosted by SFB associate PI Silvia Viana da Silva and the speaker is collaboratively funded by SFB1315 and SFB-TRR295 projects. Please let us know if you wish to meet the speaker. Read about this event and more in this month's newsletter.
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All the best for a great start in the summer semester.
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Apr 07, 2025 | 10 am - 2 pm | online
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Register Now: Postdoc School Workshops! Take your career to the next level with 12 interactive workshops on research management, self-management, science communication, and career advancement. Gain practical skills, connect with peers, and get expert guidance to shape your career path. Sign up now and secure your spot!
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More information about all available workshops >>here
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The Online Competence Tool (OCT) offered by the Postdoc Academy is specifically created for postdoctoral and doctoral researchers. It is a helpful online resource that allows you to evaluate and enhance your professional skills.
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Discover your strengths, identify areas for growth, and receive personalized feedback to aid in your career development.
Start your self-assessment now here >>
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Towards closed-loop deep brain stimulation for the treatment of Alzheimer’s disease
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Apr 15, 2025 | 4 pm CET | BCCN Lecture Hall Philippstraße 13/Haus 6 | ZOOM ID: 7754910236
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Alzheimer’s disease (AD) has very limited treatment options and therapies to prevent or reverse neurodegeneration remain elusive. Deep brain stimulation (DBS), whereby high-frequency pulses of electricity are delivered continuously to a specific part of the brain, has been trialled as an experimental treatment for AD. In AD patients, DBS has been targeted at a group of fibres called the fornix, which carry signals to and from the hippocampus; a crucial region for encoding and recalling memory. Fornix-DBS has been shown to be safe and modulate hippocampal markers of synaptic plasticity, but is not reliably effective when delivered using the standard, continuous high frequency pulses that are effective in other disorders. We propose that a different approach is required in AD, whereby closed-loop stimulation is used to restore key activities disrupted by the primary degenerative process. Closed-loop stimulation uses real-time tracking of specific aspects of neural signals to control when electrical pulses are delivered. .... Read more >>
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Equal Opportunity and Diversity
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Girls' Day 2025
Apr 3, 2025 | 9 am – 3:30 pm | Berlin Museum of Medical History, Virchowweg 17 | Charité CrossOver-CCM, Virchowweg 6, @AG Larkum | Fenster des Wissenschaft, CCM – CCO Charitéplatz 1, 10117 Berlin
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We are pleased to host our 5th annual Berlin-Bochum Memory Alliance Girls'Day in Berlin.
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Journal Club Drivers
This month DRIVERS is reading
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T. Ross-Hellauer, et al. 2024. Understanding the Social and Political Dimensions of Research(ER) Assessment: Evaluative Flexibility and Hidden Criteria in Promotion Processes at Research Institutes
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Meeting-ID: 957 6165 3396, Kenncode: 487086
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Foto – Stiftung Planetarium Berlin
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Berlin Brains Exploring the brain's cell types and communication mechanisms
Apr 9-13, 2025 | Zeiss-Großplanetarium, Prenzlauer Allee 80, 10405 Berlin
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"Rund um den 13. April 2025 feiern wir mit den Thementagen »Unsichtbare Welten: Vom Mikrokosmos zum Universum« das 400-jährige Jubiläum des Mikroskops – eine bahnbrechende Erfindung, die wie das Teleskop unseren Blick auf naturwissenschaftliche Zusammenhänge revolutioniert hat. Erleben Sie in Workshops, Fulldome-Programmen, Vorträgen und Live-Performances eine spannende Reise vom Mikrokosmos des Lebens bis in die unendlichen Weiten des Universums."
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Apr 10, 2025 | 7.30 pm | Zeiss-Großplanetarium, Prenzlauer Allee 80, 10405 Berlin
"The mammalian brain consists of many different types of cells that fulfill specific tasks. The most important cell type that controls all communication in the nervous system is the neuron. Melissa Herman and Seulkee Yang are investigating how these different types of neurons become specialized in their function during development. For the defined neuron types, they are investigating how they differ in their primary functions – for example, in the release of neurotransmitters for communication. In their talk with Jochen Müller, they show how important the description of these fundamental processes is for understanding how our brain functions in health and disease."
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Berlin-Bochum Memory Alliance
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Berlin-Bochum Memory Alliance Eearly Career Researcher Meeting, Berlin 2025
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Thanks so much to our early career researchers from Berlin and Bochum, our student coordinator Lisa Velenosi, the SFB's smart figure gallery curator Anna Nasr, and Berlin co-organizer Alexandra Tzilivaki (A01 PhD) for hosting a successful meeting in March. Congratulations for winning the science slam!
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GEM 2025 - Generative Episodic Memory
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June 2 - 4, 2025 | Ruhr University Bochum | Universitätsstraße 150, 44801 Bochum
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https://journals.aps.org/prx/abstract/10.1103/PhysRevX.14.041047
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Episodic memories are widely regarded as memories of personally experienced events. Early concepts about episodic memory were based on the storage model, according to which experiential content is preserved in memory and later retrieved. However, overwhelming empirical evidence suggests that the content of episodic memory is – at least to a certain degree – constructed in the act of remembering. [...] Read more here >>
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The call for abstracts is open!
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Deadlines: Call for abstracts 15.03.2025 | Registration 30.04.2025
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For more information visit >>
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Coupling of mitochondrial state with active zone plasticity in early brain aging
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Fei L, Liang Y, Kintscher U, Sigrist SJ
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Redox Biol. 79:103454 (2025)
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Blobby is a synaptic active zone assembly protein required for memory in Drosophila
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Lützkendorf J, Matkovic-Rachid T, Liu S, Götz T, Gao L, Turrel O, Maglione M, Grieger M, Putignano S, Ramesh N, Ghelani T, Neumann A, Gimber N, Schmoranzer J, Stawrakakis A, Brence B, Baum D, Ludwig K, Heine M, Mielke T, Liu F, Walter AM, Wahl MC, Sigrist SJ
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Nat Commun. 16(1):271 (2025)
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CSF biomarkers are differentially linked to brain areas high and low in noradrenaline, dopamine and serotonin across the Alzheimer’s disease spectrum
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Haag L, Lancini E, Yakupov R, Ziegler G, Yi YJ, Lüsebrink F, Glanz W, Peters O, Spruth EJ, Altenstein S, ..., Düzel E, Betts MJ, Hämmerer D
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Brain Commun. 7(1):fcaf031 (2025)
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Institut für Biologie
Humboldt-Universität zu Berlin
SFB1315 Speaker Matthew Larkum, Deputy Speaker Richard Kempter.
Management & Coordination
Mary Louise Grossman.
Office: Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin
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